What’s D-mannose granule ?

D-mannose is a naturally occurring simple sugar that your body utilizes to help cleanse the urinary tract and maintain a healthy bladder lining. It’s metabolized only in small amounts, with excess amounts rapidly excreted in urine, so it won’t interfere with healthy blood sugar regulation. Clinical studies have demonstrated that, when taken regularly, it promotes normal urinary tract function by cleansing and maintaining the healthy of the bladder lining.

For D-mannose, there is two kinds of specifications. Such as Powder and Granule.

Usage of D-mannose Granule

D-mannose powder is used for Capsules and Sachets.

D-mannose granule is used for directly in Tablets. Most of the Europe and United States customers purchase the products from us every year large quantity.

Health Benefits of D-Mannose

Helps Treat CDGS Type 1b

D-mannose granule or powder can help treat a rare genetic disorder called carbohydrate-deficient glycoprotein syndrome type 1b because people with this condition don’t produce enough, or any, mannose naturally.

May Help Prevent Urinary Tract Infections

Over 50% of adult women will get a UTI in their lifetime, making UTIs the most common type of outpatient infection.

The infection is typically treated with antibiotics, but researchers are interested in D-mannose as an alternative treatment that won’t promote the growth of antibiotic-resistant bacteria.

May Promote Gut Health

D-mannose may also act as a prebiotic—a dietary fiber that feeds the good bacteria in your gut. Bacteria in the large intestine ferment (break down) prebiotics, helping good bacteria thrive, producing beneficial short-chain fatty acids, improving the integrity of your gut lining, and boosting immune health.

Unlike glucose and fructose, D-mannose is a sugar that may reduce rather than increase inflammation in the gut.

In rodent-based studies, D-mannose granule or powder increased the Bacteroidetes to Firmicutes ratio in the gut, which is notable because low levels of Bacteroidetes are linked with inflammatory bowel disease (IBD).

Sources

Natural sources can be from birch trees, palm kernels, potato, corn or fruits such as cranberries and pineapples. Synthetic sources such d-fructose or d-glucose or pure starch through bio-conversions are inexpensive starting materials and widely available.

The production of D-mannose can also introduce additives, in particular if taken in capsule form. Silica, magnesium stearate, rice flour, artificial sweeteners and heavy metals can all be included as bulking agents or form the body of an individual tablet. This ensures cheaper mass production. Do your research first especially if you have allergy issues or are following a preferred regime of avoidance such as soy, gluten or GM products.

Sadly sometimes price does reflect quality of manufacture and purity of product so buyer beware.

When researching a brand look at the amount of pure D-mannose in each pot or tablet. The higher the better. A teaspoon of powder should offer around 2000 mg and a tablet around 500mg. And remember Cranberry products are not the same as D-Mannose. Cranberry extract and juice has been shown not to be effective against recurrent and chronic UTI.

D-mannose for UTIs

Some research suggests that D-mannose may play a part in treating active UTIs and preventing them from developing in the future.

Indeed, a 2022 study found that D-mannose effectively treated acute uncomplicated UTIs and prevented recurrent UTIs, with similar results to antibiotics, in several studies.

Researchers tested whether it could help prevent recurrent urinary tract infections (UTIs) in women with frequent UTIs. Two groups were randomly given d-mannose or a placebo and monitored for six months. However, 51% of the women taking d-mannose and 56% of those taking the placebo still contacted their doctor for UTI treatment during the study.

Ultimately, the findings about D-mannose are inconsistent and more studies are necessary to determine whether it is a useful treatment for UTIs. Without these studies, it is not clear what the dosage of D-mannose should be or whether it may interact with other medications or cause side effects.

Dosage

Due to the lack of research to date, it is difficult to determine either the right dosage of D-mannose granule or the form in which people should take it.

It is likely that the correct dosage for treating an active UTI will differ from that for preventing UTIs from recurring.

Some studies indicate that a dose level of 0.2 g/kg of body weight seems to be the upper limit for daily consumption of D-mannose for long-term use, as higher doses may cause gastrointestinal disturbances.

D-mannose Granule-All You Need To Know